Akshara Kulkarni
Specialises In (based on submitted proposals)
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keyboard_arrow_downDeep genomics of type 2 Diabetes
20 Mins
Talk
Advanced
Type 2 diabetes mellitus has been at the forefront of human diseases and phenotypes studied by
new genetic analyses. Thanks to genome-wide association studies, we have made substantial
progress in elucidating the genetic basis of type 2 diabetes.This tutorial summarizes the concept, history, and recent discoveries produced by genome-wide association studies for type 2 diabetes and glycemic traits, with a focus on the key notions we have gleaned from these efforts. Genome-wide association findings have illustrated novel pathways, pointed toward fundamental biology, confirmed prior epidemiological observations, and provided possible targets for pharmacotherapy and pharmacogenetic clinical trials.
Deep neural networks can be trained to detect Type 2 diabetes using a few biochemical and anthropogenic measurements. Such a network can then be used to predict onset of diabetes in other patients with access to these parameters. The tutorial will discuss a few other applications of deep learning in genomics of type 2 diabetes.
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