Institute of Bioinformatics and Applied Biotechnology (IBAB)
Member since 3 months
With a background in Physics and Electronics from the Bharathidasan University,Trichy, Dr.Vijayalakshmi Mahadevan completed her Ph.D. from the National Centre for Biological Sciences- Tata Institute of Fundamental Research( NCBS-TIFR), Bangalore. She was an Assistant Professor in the School of Electrical and Electronics Engineering at SASTRA Deemed University in Thanjavur and a TCS Chair Professor of Bioinformatics and Associate Dean of the School of Chemical & Biotechnology.She was the Group Lead of the Chromatin and Epigenetics group also headed the Department of Bioinformatics from 2008 to 2016 besides being affiliated to the Centre for Nanotechnology and Advanced BBiomaterials (CeNTAB) at SASTRA. Dr.Vijayalakshmi was also a Research Mentor in the National Network for Mathematical and Computational Biology (NNMCB), India from 2013 and was a Research Mentor – Research Science Initiative (RSI) of the IIT-Madras, Chennai Mathematical Institute, SASTRA University, Thanjavur, PSBB Group of Schools, Chennai and Centre for Excellence in Education, McLean,USA to promote scientific research among school children.
Her research is focused on understanding epigenetic signalling in disease and during apoptosis. Her laboratory uses next generation sequencing approaches, live cell imaging and high throughput microscopy to dissect the role of chromatin modifications during the onset of diseases and their progression. The group also employs a range of bioinformatics approaches, molecular simulations, image informatics, and pathway mapping strategies to understand chromatin dynamics and signalling. Her group actively collaborates with tumor pathology Departments in Germany and with simulation groups in the US to address the different dimensions controlling chromatin dynamics. More…